Table of Contents

Foreword: The Implementation of Cancer Control in the 21st Century (Part 1)
Otis W. Brawley

Foreword: The Implementation of Cancer Control in the 21st Century (Part 2)
Electra D. Paskett

Section I: An Introduction to Implementation Science Across the Cancer Control Continuum

1A. An Orientation to Implementation Science in Cancer
David A. Chambers, Wynne E. Norton, and Cynthia A. Vinson

1B. A History of the National Cancer Institute's Support for Implementation Science Across the Cancer Control Continuum: Context Counts
Jon Kerner, Russell E. Glasgow, and Cynthia A. Vinson

2. Evidence-Based Cancer Practices, Programs, and Interventions
Maria E. Fernandez, Patricia Dolan Mullen, Jennifer Leeman, Timothy J. Walker, and Cam Escoffery

3. Theories, Frameworks, and Models in Implementation Science in Cancer
Ted A. Skolarus, Rachel G. Tabak, and Anne E. Sales

4. Measures and Outcomes in Implementation Science
Cara C. Lewis, Kayne D. Mettert, Caitlin N. Dorsey, and Bryan J. Weiner

5. Study Design, Data Collection, and Analysis in Implementation Science
Marisa Sklar, Joanna C. Moullin, and Gregory A. Aarons

6. Implementation Strategies
Byron J. Powell, Krystal G. Garcia, and Maria E. Fernandez

Section II: Implementation Case Studies in Cancer Prevention and Control
7. Cancer Prevention and Public Health Promotion: Overview of Case Studies
Lisa M. Klesges

Case Study 7A: Implementation Strategies for Increasing Rates of Human Papillomavirus Vaccination
Robin C. Vanderpool, Heather M. Brandt, and Meagan R. Pilar

Case Study 7B: Cancer Prevention Through Scaling-Up the Process of Evidence-Based Decision-Making in a State Health Department
Peg M. Allen, Linda J. Ahrendt, Kiley A. Hump, and Ross C. Brownson

Case Study 7C: Implementing Evidence-Based Media Engagement Practices to Address Cancer Disparities
Racquel E. Kohler, Shoba Ramanadhan, and K. Viswanath

Case Study 7D: Dissemination and Implementation Science in Retail Tobacco Control Policy
Todd B. Combs, Laura Brossart, Kurt M. Ribisl, and Douglas A. Luke

8. Cancer Detection and Screening: Overview of Case Studies
Gloria D. Coronado

Case Study 8A: The FluFIT Program: A Colorectal Cancer Screening Intervention Designed and Tested for Successful Implementation
Michael B. Potter, Debbie Kirkland, Judith M.E. Walsh, Carol P. Somkin, Vicky Gomez, and Lawrence W. Green

Case Study 8B: Implementation of an Evidence-Based Tobacco Use Treatment Intervention in the Context of Lung Cancer Screening
Jaime Ostroff and Donna Shelley

9. Provider-Level Factors Influencing Implementation: Overview of Case Studies
Alex H. Krist and Vivian Jiang

Case Study 9A: Treatment for Early Stage Prostate Cancer: The Need to Implement Shared Decision-Making
Sarah C. Kobrin and Alex Conway

Case Study 9B: Integrating Concurrent Palliative Care into Cancer Care Delivery Settings
Meagan Whisenant and Kathi Mooney

Case Study 9C: Enhancing Fidelity to Cancer Treatment Guidelines
Kathy J. Helzlsouer and Arti Patel Varanasi

10. Organization- and System-Level Factors Influencing Implementation: Overview of Case Studies
Stephanie B. Wheeler
Case Study 10A: Integrating Patient-Reported Outcomes into Routine Cancer Care Delivery
Angela M. Stover

Case Study 10B: Patient Navigation and Cancer Care Delivery
Harold P. Freeman and Melissa A. Simon

Case Study 10C: Implementing Distress Screening in a Community and Veteran's Administration Oncology Clinic
Paul Montgomery, Nicole Thurston, Michelle Betts, and C. Scott Smith

Case Study 10D: Implementing Lynch Syndrome Screening in the Veterans Health Administration
Maren T. Scheuner, Marcia Russell, Jane Peredo, Alison B. Hamilton, and Elizabeth M. Yano

Chapter 11: Cancer Survivorship: Overview of Case Studies
Julia H. Rowland

Case Study 11A: Implementing an Evidence-Based Exercise Program for Breast Cancer Survivors
Kathryn H. Schmitz and Rinad Beidas

Case Study 11B: Using an Implementation Science Approach to Study and Improve Cancer Survivors' Employment Outcomes
Janet S. de Moor, Catherine M. Alfano, Erin E. Kent, Lynne Padgett, and Melvin Grimes

Case Study 11C: The Challenge of Implementing Survivorship Care Plans
Sarah A. Birken, Erin E. Hahn, Yan Yu, Emily Haines, Deborah K. Mayer, and Brian Mittman

12. Cancer in the Global Health Context: Overview of Case Studies
Sudha Sivaram

Case Study 12A: Adopting the PREVENTABLE Model: A Multistep Approach to Changing a Secondary Cervical Cancer Prevention Paradigm in El Salvador
Mauricio Maza, Karla Alfaro, Julia Gage, and Miriam Cremer

Case Study 12B: Implementing Evidence-Based Tobacco Use Treatment in Community Health Centers in Vietnam
Mark Parascandola and Donna Shelley

Case Study 12C: Assessing the Community Context when Implementing Cervical Cancer Screening Programs
Prajakta Adsul and Purnima Madhivanan

Section III: Emerging Issues in Implementation Science across the Cancer Control Continuum

13. Using Precision Medicine to Improve Health and Healthcare: The Role of Implementation Science
Mindy Clyne, Amy Kennedy, and Muin J. Khoury

14. Harnessing Big Data-Based Technologies to Improve Cancer Care
Gurvaneet S. Randhawa and Edwin A. Lomotan

15. Scaling-Up Cancer Control Innovations
Nancy C. Edwards, Barbara L. Riley, and Cameron D. Willis

16. Sustainability of Cancer Practices and Programs
Shannon Wiltsey Stirman and James W. Dearing

17. Overuse and De-Implementation of Inappropriate Cancer Screening, Diagnosis, and Treatment Practices
Maryam Doroudi, Barnett S. Kramer, and Paul F. Pinsky

18. Partnerships and Networks to Support Implementation Science
K. Vish Viswanath, Racquel Kelly Kohler, and Shoba Ramanadhan

19. Cost-Effectiveness Analysis in Implementation Science
Heather Taffet Gold

20. Future Directions in Implementation Science Across the Cancer Continuum
Wynne E. Norton, Cynthia A. Vinson, and David A. Chambers
Resources

Glossary

Index

About the Author

David A. Chambers, D.Phil, is Deputy Director for Implementation Science in the Division of Cancer Control and Population Sciences at the National Cancer Institute, where he manages a team focusing on efforts to build and advance the field of implementation science through funding opportunity announcements, training mechanisms, dissemination platforms, and enhancement of partnerships and networks to integrate research, practice and policy. Dr. Chambers publishes on
strategic research directions in implementation science, and serves as a plenary speaker at numerous scientific conferences. He received his A.B. degree (with Honors) in Economics from Brown
University (1997), and an M.Sc. (1998) and D.Phil degree (2001) in Management Studies (Organizational Behaviour) from Oxford University (UK.)

Cynthia A. Vinson, PhD, MA, is a Senior Advisor for Implementation Science in the Division of Cancer Control and Population Sciences at the National Cancer Institute. Dr. Vinson is involved with building and sustaining the field of implementation science to enhance the integration of evidence-based programs in cancer control in public health and clinical practice. In this role, she is responsible for working both within NCI and with other agencies and organizations at the local, state,
national, and international level to translate research funded by DCCPS into practice. Dr. Vinson received her PhD in Public Administration and Health Policy at George Washington University, and her MPA in
Public Administration/International Development from Rutgers, the State University of New Jersey.

Wynne E. Norton, PhD, is a Program Officer for Implementation Science in the Division of Cancer Control and Population Sciences at the National Cancer Institute. Dr. Norton's research is focused on advancing the science of implementation of evidence-based practices and programs in cancer care delivery and public health. Dr. Norton received her MA (2008) and her PhD (2009) in Social Psychology from the University of Connecticut. Prior to joining the NCI, Dr. Norton was an Assistant Professor in
a School of Public Health (2009-2015), during which time her program of research was funded by NIH, AHRQ, Bill and Melinda Gates Foundation, and the Donaghue Foundation.