Table of Contents

Advances in Critical Care.- Effects of body position on ventilation/perfusion matching.- Chest pain.- The electrocardiogram in the emergency department.- The use of imaging to resolve difficult diagnoses.- Assessment of pain.- Titration of opioids for acute pain management.- Neonatal Mechanical Ventilation.- Extracorporeal circulation in the intensive care unit.- Clinical decision-making in the management of sepsis and septic shock.- Intracranial haemorrhage: the solution offered by recombinant factor VIIa.- An introduction to Open Source software licensing and use in anaesthesia department.- Microdialysis.- Lessons we have learnt from microdialysis in animals and humans.- Secondary brain injury — does microdialysis have a role?.- Liver graft monitoring with intrahepatic microdialysis.- Myocardial metabolism during open heart surgery, assessed with microdialysis.- Clinical Pharmacology.- The journey of a drug to the target site: what is decisive?.- The pharmacokinetics and pharmacodynamics of antimicrobial agents in intensive care unit patients as assessed by microdialysis.- Perioperative Medicine.- Anaesthetic effects on regional cerebral blood flow and metabolism: three contemporary reasons to care.- Why and when is inhalation anaesthesia better.- Analysis and instrumentations for estimating cerebral activity.- Neuroimaging pharmacology of attention and memory.- Intracranial pressure monitoring.- Improving quality of recovery.- Lung and Artificial Ventilation.- Molecular biology and lung disease What is the impact?.- Surfactant metabolism: factors affecting lipid uptake in vivo and in vitro.- Respiratory mechanics at the bedside.- PEEP and cardiac output.- Expiratory flow limitation and intrinsic PEEP.- Mechanical ventilation strategies for lung protection.- Recruitment and oxygenation.- Lung oedema in acute lung injury.- Grading severity of respiratory dysfunction, clinical correlates and indications for mechanical ventilation.- Weaning as a cardiac stress test.- Respiratory management in obese patients.- Is the acute respiratory distress syndrome a systemic disease?.- Cardiovascular Critical Care.- Invasive versus non-invasive haemodynamic monitoring in major vascular surgery.- Analysis of arterial pulse — clinical implications.- Beat-by-beat monitoring of cardiac output with pressure recording analytical method.- Haemodynamic standardisation procedures in high-risk surgery.- From Frank-Starling relationships to ventriculo-arterial coupling.- Pharmacology and selection of inotropic therapy.- Decision-making in critical care: Cardiac arrhythmias and related topics.- Management for the patient with an implanted cardiac rhythm management device.- Hypothermia in cardiac surgery.- Cardiopulmonary Resuscitation.- Pharmacological management of cardiopulmonary resuscitation.- Myocardial preservation, reperfusion injury, and postresuscitation myocardial dysfunction.- Microcirculation and Shock.- Regional blood flow distribution in septic, cardiogenic and haemorrhagic shock.- Orthogonal polarisation spectral imaging: principles, techniques, human studies.- Carbon dioxide monitoring to evaluate cell oxygenation.- The microcirculation in distress; monitoring and recruitment.- Tissue metabolism in different types of shock.- Organ dysfunction in circulatory shock — altered perfusion, metabolism or tight junctions? Do we need a shift of paradigm?.- Haemodynamic support of paediatric patients in septic shock.- Paediatric Critical Care.- Recent advances in artificial ventilation in paediatric age.- Complications in paediatric regional anaesthesia.- Home ventilation in paediatric patients with chronic respiratory failure.- Decision-making in paediatric extracranial trauma.- Developments in the treatment of postoperative pain in paediatrics.- Trauma and Emergency System.- Prehospital care: triage and primary survey.- Spine and spinal cord trauma.- Treatment of acute pneumothorax in the field.- Clinical Study Design.- Critical appraisal skills.- Literature search.- Study design.