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Survival analysis arises in many fields of study including medicine, biology, engineering, public health, epidemiology, and economics. This book provides a comprehensive treatment of Bayesian survival analysis. Several topics are addressed, including parametric models, semiparametric models based on prior processes, proportional and non-proportional hazards models, frailty models, cure rate models, model selection and comparison, joint models for longitudinal and survival data, models with time varying covariates, missing covariate data, design and monitoring of clinical trials, accelerated failure time models, models for multivariate survival data, and special types of hierarchical survival models. Also various censoring schemes are examined including right and interval censored data. Several additional topics are discussed, including noninformative and informative prior specificiations, computing posterior qualities of interest, Bayesian hypothesis testing, variable selection, model selection with nonnested models, model checking techniques using Bayesian diagnostic methods, and Markov chain Monte Carlo (MCMC) algorithms for sampling from the posteiror and predictive distributions. The book presents a balance between theory and applications, and for each class of models discussed, detailed examples and analyses from case studies are presented whenever possible. The applications are all essentially from the health sciences, including cancer, AIDS, and the environment. The book is intended as a graduate textbook or a reference book for a one semester course at the advanced masters or Ph.D. level. This book would be most suitable for second or third year graduate students in statistics or biostatistics. It would also serve as a useful reference book for applied or theoretical researchers as well as practitioners. Joseph G. Ibrahim is Associate Professor of Biostatistics at the Harvard School of Public Health and Dana-Farber Cancer Institute; Ming-Hui Chen is Associate Professor of Mathematical Science at Worcester Polytechnic Institute; Debajyoti Sinha is Associate Professor of Biostatistics at the Medical University of South Carolina.
Show moreSurvival analysis arises in many fields of study including medicine, biology, engineering, public health, epidemiology, and economics. This book provides a comprehensive treatment of Bayesian survival analysis. Several topics are addressed, including parametric models, semiparametric models based on prior processes, proportional and non-proportional hazards models, frailty models, cure rate models, model selection and comparison, joint models for longitudinal and survival data, models with time varying covariates, missing covariate data, design and monitoring of clinical trials, accelerated failure time models, models for multivariate survival data, and special types of hierarchical survival models. Also various censoring schemes are examined including right and interval censored data. Several additional topics are discussed, including noninformative and informative prior specificiations, computing posterior qualities of interest, Bayesian hypothesis testing, variable selection, model selection with nonnested models, model checking techniques using Bayesian diagnostic methods, and Markov chain Monte Carlo (MCMC) algorithms for sampling from the posteiror and predictive distributions. The book presents a balance between theory and applications, and for each class of models discussed, detailed examples and analyses from case studies are presented whenever possible. The applications are all essentially from the health sciences, including cancer, AIDS, and the environment. The book is intended as a graduate textbook or a reference book for a one semester course at the advanced masters or Ph.D. level. This book would be most suitable for second or third year graduate students in statistics or biostatistics. It would also serve as a useful reference book for applied or theoretical researchers as well as practitioners. Joseph G. Ibrahim is Associate Professor of Biostatistics at the Harvard School of Public Health and Dana-Farber Cancer Institute; Ming-Hui Chen is Associate Professor of Mathematical Science at Worcester Polytechnic Institute; Debajyoti Sinha is Associate Professor of Biostatistics at the Medical University of South Carolina.
Show more1 Introduction.- 2 Parametric Models.- 3 Semiparametric Models.- 4 Frailty Models.- 5 Cure Rate Models.- 6 Model Comparison.- 7 Joint Models for Longitudinal and Survival Data.- 8 Missing Covariate Data.- 9 Design and Monitoring of Randomized Clinical Trials.- 10 Other Topics.- List of Distributions.- References.- Author Index.
From the reviews: "The analysis of time-event data arises naturally
in many fields of study. This book focuses exclusively on medicine
and public health but the methods presented can be applied in a
number of other areas, including biology, economics and
engineering. Although several previously published texts address
survival analysis from a frequentist perspective, this book
examines solely Bayesian approaches to survival analysis. Recent
advances in computing and practical methods for prior elicitation
have now made Bayesian survival analysis of complex models
feasible. This book provides a comprehensive and modern treatment
of the subject. In addition, the authors demonstrate the use of the
statistical package BUGS for several of the models and
methodologies discussed in the book. The authors provide a
collection of theoretical and applied problems in the exercises at
the end of each chapter."
ISI Short Book Reviews, April 2002 "This is definitely a worthwhile
read for any statistician specializing in survival analysis. It is
pitched so that part of it is readily usable by the medical
statisitciann, but it will also provide stimulation for
statisticians involved in methodological development or the writing
of new software for survival analysis." International Journal of
Epidemiology "Many books have been published concerning survival
analysis or Bayesian methods; Bayesian Survival Analysis is the
first comprehensive treatment that combines these two important
areas of statistics. Ibrahim, Chen, and Sinha have made an
admirable accomplishment on the subject in a well-organized and
easily accessible fashion." Journal of the American Statistical
Association "This is one of the best combinations of advanced
methodology and practical applications that I have ever
encountered." Technometrics, May 2002 "This is a book by three
authors who are well-known for their contribution to Bayesian
survivalanalysis. … It is a good book with many areas of strength.
… There are several new methods, ideas, results, some of which are
due to the authors. There is a good discussion of historical priors
… . Other things that strike me as new are a good technical
discussion of frailty and cure models … . I have learnt a lot and
enjoyed reading the book." (Jayanta K. Ghosh, Sankhya: The Indian
Journal of Statistics, Vol. 65 (3), 2003) "This book illustrates
several Bayesian techniques to analyze survival data in biology,
medicine, public health, epidemiology, clinical trials, and
economics. … It could be used as a textbook in a graduate level
course. … In particular, I enjoyed the presentations of cure models
and cancer vaccine trials. Biostatisticians will like reading this
book from the Bayesian points of view." (Ramalingam Shanmugam,
Journal of Statistical Computation and Simulation, Vol. 74 (10),
2004) "This book offers an excellent and thorough summary of an
exciting methodological development since the seventies of the last
century. … The authors offer a gentle journey through the
archipelago of Bayesian Survival analysis. They combine in a
pleasant way theory, examples, and exercises. … I hope that this
stimulating book may tempt many readers to enter the field of
Bayesian survival analysis … ." (Ulrich Mansmann, Metrika,
September, 2004) "It offers a presentation of Bayesian methods in
Survival Analysis that is, at a time, comprehensive and suitably
balanced between theory and applications; many relevant models and
methods are illustrated and most of them are provided with detailed
examples and case studies drawn from the medical research. … The
book offers a quite up-to-date view of Bayesian Statistics and
accounts extensively for Monte Carlo-based sampling methods and for
the various methods of prior elicitation, suitable to cope with
non-parametric as well as with semi-parametric models." (Fabio
Spizzichino, Statistics inMedicine, Vol. 23, 2004) "This is not an
elementary book. … The book develops methodology and does this at a
high level, because the reader is presumed to have a mathematical
statistics background in both classical and Bayesian methods.
Happily, the book is replete with examples. This is one of the best
combinations of advanced methodology and practical applications
that I have encountered. … Computing support for the book comes
from the package called BUGS … ." (Technometrics, Vol. 44 (2),
2002) "This book provides a comprehensive treatment of Bayesian
survival analysis. Several topics are addressed, including
parametric models, semiparametric models based on prior processes,
proportional and non-proportional hazards models, frailty models,
cure rate models, model selection and comparison … . The book
presents a balance between theory and applications, and for each
class of models discussed, detailed examples and analyses from case
studies are presented whenever possible." (L’Enseignement
Mathématique, Vol. 48 (1-2), 2002) "The book is about Bayesian
survival analysis which is illustrated with examples that mostly
use the BUGS software package. … this is definitively a worthwhile
read for any statistician specializing in survival analysis. It is
pitched so that part of it is readily usable by the medical
statistician, but it will also provide stimulation for
statisticians involved in methodological development or the writing
of new software for survival analysis." (Margaret May,
International Journal of Epidemiology, Vol. 31 (2), 2002) "This
book focuses exclusively on medicine and public health but the
methods presented can be applied in a number of other areas,
including biology, economics and engineering. … This book provides
a comprehensive and modern treatment of the subject. In addition,
the authors demonstrate the use of the statistical package BUGS for
several of the models and methodologies discussed in thebook. The
authors provide a collection of theoretical and applied problems in
the exercises at the end of each chapter." (C. M. O’Brien, Short
Book Reviews, Vol. 22 (1), 2002) "Ibrahim, Chen and Sinha command
over a rich experience in both Bayesian and survival analysis.
Drawing from this experience they have put together a comprehensive
description of Bayesian methodology in survival analysis. The book
is written for researchers and graduate students. … The book is a
useful tool for practitioners who analyze survival data using
Bayesian methods." (Mathias Schaller, Statistical Papers, Vol. 47,
2005)
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