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Based on the National Academy of Sciences approach to quantitative risk assessment. Emphasizes how an accurate assessment of cancer risk must draw on a wide range of disciplines, such as biology, chemistry, physics, engineering, and the social sciences. Provides tables of Poisson confidence limit fa
Based on the National Academy of Sciences approach to quantitative risk assessment. Emphasizes how an accurate assessment of cancer risk must draw on a wide range of disciplines, such as biology, chemistry, physics, engineering, and the social sciences. Provides tables of Poisson confidence limit fa
Preface -- I. INTRODUCTION -- 1. Introduction -- 2. The Human Cancer Situation -- 3. Hazard Identification -- II. EXPOSURE AND DOSE ASSESSMENT -- 4. Exposure Assessment: General Issues -- 5. Measurement of Exposure and Dose -- 6. Modeling Exposure -- 7. Pharmacokinetics -- III. DOSE-RESPONSE ASSESSMENT -- 8. Toxicology -- 9. Mouse to Man: Extrapolation from Animals -- 10. Quick Methods: Structure-Activity Relationships and Short-Term Bioassay -- 11. Epidemiology -- 12. Combined Approaches to Dose-Response: Putting It All Together -- IV. RISK CHARACTERIZATION AND IMPLICATIONS -- 13. Characterization of Uncertainty -- 14. Risk Characterization, Communication, and Perception -- 15. Quality Assurance, Validation, and Peer Review -- 16. Implications for Risk Management -- 17. Future Directions for Quantitative Health Risk Analysis -- Index.
Morris, Samuel C.
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