Table of Contents

The Hydrocarbons

The Alkanes

The Alkenes and Alkynes

The Alicyclic Hydrocarbons

The Monocyclic Aromatic Hydrocarbons

The Polycyclic Aromatic Hydrocarbons

Alcohols and Phytosterols

Alcohols

Phytosterols

Aldehydes and Ketones

The Assertion of Aldehydes and Ketones as Ciliastatic Tobacco Smoke Components

Ciliastasis Studies with Cigarette Smoke Condensate Fractions

Ciliastasis Studies with Individual Cigarette Mainstream Smoke Components

Nose Inhalation of Environmental Tobacco Smoke vs. Mouth Inhalation of Mainstream Smoke

Carboxylic Acids

The Carboxylic Acids

The Amino Acids and Related Compounds

The Esters

The Lactones

Anhydrides

Carbohydrates and Their Derivatives

Phenols and Quinones

Phenols

Quinones

The Ethers

Nitriles

Acyclic Amines

Amides

Imides

N-Nitrosamines

Volatile N-Nitrosamines

Nonvolatile N-Nitrosamines

Tobacco-Specific N-Nitrosamines

N-Nitrosamino Acids

Tobacco-Specific N-Nitrosamines: An Exception among the Major MSS Toxicants

Direct Transfer of TSNAs from Tobacco vs. Their Formation during the Smoking Process

Infrequently Studied Tobacco and/or Smoke Secondary Amines and Their N-Nitrosamines

Flue-Curing and Tobacco-Specific N-Nitrosamines

Nitroalkanes, Nitroarenes, and Nitrophenols

Nitrogen Heterocyclic Components

Monocyclic Five-Membered N-Containing Ring Compounds

Monocyclic Six-Membered N-Containing Ring Compounds

Lactams

Oxazoles and Oxazines

Aza-Arenes

N-Heterocyclic Amines

Miscellaneous Components

Sulfur-Containing Components

Halogenated Components

Fixed and Variable Gases

Metallic and Nonmetallic Elements, Isotopes, Ions, and Salts

Elements, Isotopes, and Ions in Plants

Methods for the Detection and Identification of Metals, Ions, and Isotopes in Tobacco and Tobacco Smoke

The Transference of Elements, Isotopes, and Ions from Tobacco to Tobacco Smoke

Pesticides and Growth Regulators

Synthetic Pesticides and Plant Growth Regulator Residues on Tobacco

Naturally Occurring Plant Growth Regulators and Pesticides in Tobacco

Transfer Rates of Pesticides and Plant Growth Regulators to Mainstream Smoke

Decomposition Products of Agrochemicals in Mainstream Smoke

Methods for Analysis of Pesticides and Plant Growth Regulators

Residues of Synthetic Pesticides and Plant Growth Regulators Identified in Tobacco and Tobacco Smoke

Genes, Nucleotides, and Enzymes

Tobacco Genetics

Genes, Nucleotides, and Enzymes Identified in Tobacco

"Hoffmann Analytes"

Tobacco and/or Tobacco Smoke Components Used as Tobacco Ingredients

Pyrolysis

Individual Tobacco Types

Extracts from Tobacco

Individual Tobacco Components

Tobacco Additives

Cigarette Construction Materials (Paper, Adhesives, etc.)

Flavoring Ingredients

Carcinogens, Tumorigens, and Mutagens vs. Inhibitors, Anticarcinogens, and Antimutagens

Carcinogens, Tumorigens, and Mutagens

Anticarcinogens, Inhibitors, and Antimutagens

Alternate Exposures

Free Radicals

Introduction

Analytical Methods for Determination of Free Radicals

Free Radicals in Tobacco Smoke

Historical Review of Free Radical Research on Cigarette Smoke

Proposed Mechanisms for the Generation of Free Radicals in Mainstream Smoke

Summary

Bibliography

Index

About the Author

Perfetti and Perfetti, LLC, Winston-Salem, North Carolina, U

Reviews

! the real value of the book will turn out in its daily use and it has all chances to become the standard reference book (perhaps 'The Bible') of all tobacco scientists. -- Dr. Gerhard Scherer, Editor of Beitrage zur Tabakforschung International, Bonn, Germany I highly recommend this book as an indispensable reference source for tobacco and smoke chemists as well as other scientists involved in the study of tobacco and its products. The compilation of proper chemical names, common names, Chemical Abstract Service numbers (CAS No.), and structures alone are worth the purchase price. --Charles R. Green, Ph.D., Retired Senior Principal Scientist, R. J. Reynolds Tobacco Company, Winston-Salem, North Carolina Many congratulations on this monumental piece of work. --Dr. Chuan Liu, Senior Scientist, Applied Research, Group Research & Development, British American Tobacco, Southampton, United Kingdom As a statistician I would like to forecast: There will not be any other comprehensive work in the next 30-50 years about this topic -- Rodgman -- Perfetti will be the definitive book. --Prof. Dr. Wolf-Dieter Heller, Karlsruhe, Germany as a reference text on a laboratory shelf it will prove essential and take its place alongside the other CRC publications. --M. Cooke, Chromatographia 2010, 71