Table of Contents

I- Colorectal Cancer:


1. Epidemiology of Colorectal Cancer: Amit Surya Narayan, Christina Wu, and Walid L. Shaib


2. Diagnosis and Staging of Colorectal Cancer: Amit Surya Narayan, Christina Wu, and Walid L. Shaib


3. Molecular Diagnostic Guidelines for Colorectal Cancer: Christine Wu, Walid L. Shaib, and Ibrahim Halil Sahin


4. How I Treat Early Stage Colon Cancer Through Surgery: Mark W. Arnold


5. How I Treat Early Stage Colon Cancer with Adjuvant Therapy: Who and How Long?: Francesca Battaglin and Heinz-Josef Lenz


6. How I Treat Early Stage Rectal Cancer with Neoadjuvant Therapy with Radiation: Nikhil Sebastian and Terence Williams


7. How I Treat Early Stage Rectal Cancer Through Surgery: Nitin Mishra


8. How I Treat Early Stage Rectal Cancer with Adjuvant Therapy: Gabriel A. Brooks


9. How I Treat Oligometastatic Colorectal Cancer Through Surgery: Rory L. Smoot and David M. Nagorney


10. How I Treat Oligometastatic Colorectal Cancer with Neoadjuvant Chemotherapy: Marwan Fakih


11. How I Treat Oligometastatic Colorectal Cancer Through Local Non-Surgical Approaches: Sadeer Alzubaidi, Alex Wallace, and Rahmi Oklu


12. How I Treat Oligometastatic Colorectal Cancer with Adjuvant Chemotherapy: Andrea Cercek and Gustavo dos Santos Fernandes


13. How I Treat Oligometastatic Colorectal Cancer with Debulking/HIPEC in Limited Peritoneal Disease: Ed Levine


14. How I Treat Metastatic Colorectal Cancer with Chemotherapy and Choice of Biologics: Kristen K. Ciombor and Satya Das


15. How I Treat Metastatic Colorectal Cancer with Maintenance Therapies: Sakti Chakrabarti and Joleen M. Hubbard


16. How I Treat Metastatic Colorectal Cancer with Emerging Therapeutic Strategies: Niharika B. Mettu and John H. Strickler


17. How I Treat Metastatic Colorectal Cancer with Immunotherapy: Michael Lam and Shubham Pant


II- Pancreatic Cancer:


18. Epidemiology of Pancreatic Cancer: Mehmet Akce, Alexandra G. Lopez-Aguiar, David A. Kooby, Field F. Willingham, Gregory B. Lesinski, and Shishir K. Maithel


19. Biological Basis for Pancreatic Cancer: Brandon Ware, Mehmet Akce, Alexandra G. Lopez-Aguiar, David A. Kooby, Field F. Willingham, Shishir K. Maithel, Gregory B. Lesinski


20. Diagnosis and Staging of Pancreatic Cancer: Ramzi Mulki, Parit Mekaroonkamol, Alexandra G. Lopez-Aguiar, Gregory B. Lesinski, David A. Kooby, Mekmet Akce, Shishir K. Maithel, and Field F. Willingham


21. The Role and Timing of Surgery in Pancreatic Cancer: Mark Truty


22. How I Treat Resectable PancreaticCancer with Adjuvant Therapy: Philip A. Philip and Mandana Kamgar


23. How I Treat Resectable Pancreatic Cancer with Neoadjuvant Therapy: Davendra P. S. Sohal


24. How I Treat Borderline Resectable and Locally Advanced Pancreatic Cancer: Hao Xie, Tanios Bekaii-Saab, and Wen Wee Ma


25. How I Treat Metastatic Pancreatic Cancer with Chemotherapy: Benjamin A. Krantz and Eileen M. O’Reilly


26. How I Treat Metastatic Pancreatic Cancer with Emerging Targets: Benjamin A. Krantz and Eileen M. O’Reilly


III- Hepatocellular Cancer:


27. Epidemiology of Hepatocellular Cancer: Safi Shahda and Bert O’Neil


28. Diagnosis and Staging of Hepatocellular Cancer: Safi Shahda and Bert O’Neil


29. Cellular and Molecular Pathology of Hepatocellular Cancer: Safi Shahda and Bert O’Neil


30. How I Treat Early-Stage Hepatocellular Cancer Through Transplant: Emmanouil Girogakis and Amit K. Mathur


31. How I Treat Early-Stage Hepatocellular Cancer Through Surgery: Rachel M. Lee and Kenneth Cardona


32. How I Treat Early-Stage Hepatocellular Cancer with Local Non-Surgical Approaches: Junaid Raja and Hyun S. Kim


33. How I Treat Early-Stage Hepatocellular Cancer with Local Non-Surgical Approaches: Jonathan B. Ashman


34. How I Treat Advanced Hepatocellular Cancer with Multikinase Inhibitors and Other Targeted Therapies: Kabir Mody and Ghassan K. Abou-Alfa


35. How I Treat Advanced Hepatocellular Cancer with Immunotherapy: Olatunji B. Alese and Katerina Zakka


IV- Gastric and Esophageal Cancer:


36. Epidemiology of Gastric and Esophageal Cancer: Mohamad Bassam Sonbol and Daniel H. Ahn


37. Diagnosis and Staging of Gastric and Esophageal Cancer: Mohamad Bassam Sonbol and Daniel H. Ahn


38. Molecular Diagnostic Guidelines of Gastric and Esophageal Cancer: Mohamad Bassam Sonbol and Daniel H. Ahn


39. How I Treat Early Stage Gastric and Esophageal Cancer with Neoadjuvant Therapy: William A. Stokes and Karyn A. Goodman


40. How I Treat Early Stage Gastric and Esophageal Cancer with Surgery: Sajid A. Khan, Vadim Kurbatov, and Mitchell C. Posner


41. How I Treat Metastatic Gastric and Esophageal Cancer with Chemotherapy and Choice of Biologics: Mehmet Akce


42. How I Treat Metastatic Gastric and Esophageal Cancer with Immunotherapy: Curtis R. Chong and Yelena Y. Janjigian


V- Rare Gastrointestinal Cancers:


43. Molecular Diagnostic Guidelines of Cancers of the Bile Ducts and Gallbladder: Talal Hilal and Mitesh J. Borad


44. Surgery for Early-Stage Cancers of the Bile Ducts and Gallbladder: Jordan Cloyd, Charlie Kimbrough, and Timothy M. Pawlik


45. Adjuvant Therapy for Early-Stage Cancers of the Bile Ducts and Gallbladder: Flavio G. Rocha


46. Chemotherapy for Advanced Cancers of the Bile Ducts and Gallbladder: Jonathan Whisenant


47. Emerging Therapies for Advanced Cancers of the Bile Ducts and Gallbladder: Madappa Kundranda and Milind Javle


48. Neuroendocrine Tumors: Jonathan Strosberg


49. Early-Stage Anal Cancer: Clayton A. Smith, Nitesh Rana, and Lisa A. Kachnic


50. Metastatic Anal Cancer: Saivaishnavi Kamatham, Faisal Shahjehan, and Pashtoon M. Kasi


51. Gastrointestinal Stromal Tumors (GIST): Kantha Ratnam Kolla and Mahesh Seetharam


VI- Special Clinical Considerations for Gastrointestinal Cancer Patients:


52. Nutritional Needs for Gastrointestinal Cancer Patients: Tiffany Barrett


53. Palliative Carefor Gastrointestinal Cancer Patients: Angelia Curseen


54. Care for Elderly Gastrointestinal Cancer Patients: Grant R. Williams and Hanna K. Sanoff


55. Survivorship Care for Gastrointestinal Cancer Patients: Nataliya V. Uboha, Mary Mulkerin, Stephanie L. Fricke, and Noelle K. LoConte

About the Author

Tanios Bekaii-Saab, MD, FACP, is Professor of Medicine, Senior Associate Consultant of Hematology and Oncology, and Co-Leader of the Gastrointestinal Cancer Program at the Mayo Clinic Cancer Center in Scottsdale, Arizona.