This text has been written as a practical guide, based on the author’s experience over the last 40 years of daily clinical practice and aiming to place the modern approach to the management of infertility in the context of sound theory and evidence-based therapy. It provides the reader with a comprehensive classification of the causes of infertility, their investigation, and their management. This new edition covers many advances in the understanding and management of infertility and other updates to practice--for example, a greater understanding of the pathophysiology of ovarian aging and ovarian reserve testing; the classification of disorders of ovulation and management of polycystic ovary syndrome; the refinement of regimens for superovulation, improved embryo culture systems, and the use of artificial intelligence for the selection of embryos; assessments for endometrial receptivity and management of recurrent implantation failure; pre-implantation genetic testing (PGT) as a therapeutic tool opening up the possibility for aneuploidy screening; as well as the latest thoughts on nutritional health, periconception care, and the exciting new world of the microbiome.
This text has been written as a practical guide, based on the author’s experience over the last 40 years of daily clinical practice and aiming to place the modern approach to the management of infertility in the context of sound theory and evidence-based therapy. It provides the reader with a comprehensive classification of the causes of infertility, their investigation, and their management. This new edition covers many advances in the understanding and management of infertility and other updates to practice--for example, a greater understanding of the pathophysiology of ovarian aging and ovarian reserve testing; the classification of disorders of ovulation and management of polycystic ovary syndrome; the refinement of regimens for superovulation, improved embryo culture systems, and the use of artificial intelligence for the selection of embryos; assessments for endometrial receptivity and management of recurrent implantation failure; pre-implantation genetic testing (PGT) as a therapeutic tool opening up the possibility for aneuploidy screening; as well as the latest thoughts on nutritional health, periconception care, and the exciting new world of the microbiome.
Foreword. Preface. About the Author. Epidemiology of Infertility, 21st-Century Considerations and the Covid-19 Pandemic. Prevention of Infertility. Planning a Pregnancy and Preconception Care. Obesity and Reproduction. 5 Investigating Infertility. Anovulatory Infertility and Ovulation Induction. Polycystic Ovary Syndrome. Premature Ovarian Insufficiency and Oocyte Donation. Endometriosis. Tubal Infertility, Fibroids and Uterine Factors. Male Factor Infertility. Unexplained Infertility. Fertilisation. Fertility Preservation. Pre-Implantation Genetic Testing and Emerging Technologies. Complications of Ovarian Stimulation. Counselling and Modern Families. Ethical and Religious Issues. Health Outcomes of Children Born after Assisted Conception. Miscarriage and Ectopic Pregnancy. Recurrent Miscarriage and Recurrent Implantation Failure. Alternative Therapies and "Add-Ons". When to Stop Treatment and Other Options. Appendix: Daily Vitamin and Mineral Requirements (See Chapter 3). Books for Further Reading. Index.
Adam Balen MB, BS, MD, DSc, FRCOG is a full time Consultant in Reproductive Medicine at Leeds Teaching Hospitals NHS Trust, Professor of Reproductive Medicine and Surgery at St. James’ University Hospital, Consultant and the Clinical Lead at Leeds Fertility, a partner at Balance Fertility, former Chair of the British Fertility Society, and the Royal College of Obstetricians and Gynaecologist's spokesperson for fertility.
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