Promotional Information

Part of a series offering the most comprehensive coverage of developmental neuroscience available, covering molecular development through to cognition and disease

Table of Contents

Part I: Induction and Patterning of the CNS and PNS
1. Telencephalon Patterning
S. Tole, J. Hébert
2. Morphogens, Patterning Centers, and their Mechanisms of Action
E.A. Grove, E.S. Monuki
3. Midbrain Patterning: Isthmus Organizer, Tectum Regionalization, and Polarity Formation
H. Nakamura
4. Area Patterning of the Mammalian Cortex
D.D.M. O'Leary, A.M. Stocker, A. Zembrzycki
5. The Formation and Maturation of Neuromuscular Junctions
C.R. Hayworth, R.J. Balice-Gordon
6. Neural Induction of Embryonic Stem/Induced Pluripotent Stem Cells
K. Brennand, F. Gage
7. Spinal Cord Patterning
W.D. Gifford, M. Hayashi, M. Sternfeld, J. Tsai, W.A. Alaynick, S.L. Pfaff
8. Patterning of the Diencephalon
L. Puelles, S. Martinez
9. Neural Induction Embryonic Stem Cells
C. Kintner, A. Hemmati-Brivanlou
10. Plan of the Developing Vertebrate Nervous System: Relating Embryology to the Adult Nervous System (Prosomere Model, Overview of Brain Organization)
L. Puelles
11. Cerebellar Patterning
J.K. Fahrion, Y. Komuro, N. Ohno, Y. Littner, C. Nelson, T. Kumada, B. Lamb, H. Komuro
12. Hox Genes and Neural Patterning in Drosophila
P.A. Kuert, H. Reichert
13. Induction and Patterning of Neural Crest and Ectodermal Placodes and their Derivatives
J. Begbie

Part II: Generation of Neuronal Diversity
14. Cell Biology of Neuronal Progenitor Cells
S. Temple, Q. Shen
15. Cell Cycle Regulation in Brain Construction
M. Crespo, M.E. Ross
16. Regulation of Neuronal Survival by Neurotrophins in the Developing Peripheral Nervous System
A.M. Davies
17. Notch and Neural Development
J.J. Breunig, B.R. Nelson
18. bHLH Factors in Neurogenesis and Neuronal Subtype Specification
H.C. Lai, D.M. Meredith, J.E. Johnson
19. Environmental Cues and Signaling Pathways that Regulate Neural Precursor Development
A. Gauthier-Fisher, F.D. Miller
20. Specification of Neural Crest- and Placode-Derived Neurons
L. Sommer
21. The Specification and Generation of Neurons in the Ventral Spinal Cord
M. Matise, K. Sharma
22. Neurogenesis in the Cerebellum
V.V. Chizhikov, K.J. Millen
23. The Generation of Midbrain Dopaminergic Neurons
S.R.W. Stott, S.-L. Ang
24. Neurogenesis in the Basal Ganglia
J.L.R. Rubenstein, K. Campbell
25. Specification of Cortical Projection Neurons: Transcriptional Mechanisms
J.L. MacDonald, R.M. Fame, E. Azim, S.J. Shnider, B.J. Molyneaux, P. Arlotta, J.D. Macklis
26. The Generation of Cortical Interneurons
R. Batista-Brito, G. Fishell
27. Specification of Retinal Cell Types
R.B. Hufnagel, N.L. Brown
28. Neurogenesis in the Postnatal VZ-SVZ and the Origin of Interneuron Diversity
A. Alvarez-Buylla, F. Merkle, L. Fuentealba
29. Neurogenesis in the Damaged Mammalian Brain
M. Nakafuku, A. Grande
30. Neurogenesis in the Nematode Caenorhabditis elegans*
O. Hobert
31. Development of the Drosophila Embryonic Ventral Nerve Cord: From Neuroectoderm to Unique Neurons and Glia
J. Benito-Sipos, M. Baumgardt, S. Thor
32. Neurogenesis in Zebrafish
A. Alunni, M. Coolen, I. Foucher, L. Bally-Cuif

Part III: Development of Glia, Blood Vessels, Choroid Plexus, Immune Cells in the Nervous System
33. ‘Glial’ Biology: Has it Come to the Beginning of the End?
D. Rowitch, A. Alvarez-Buylla
34. Neural Stem Cells Among Glia
A. Alvarez-Buylla, A. Kriegstein
35. Structure and Function of Myelinated Axons
S.A. Buffington, M.N. Rasband
36. Mechanisms of Astrocyte Development
A.V. Molofsky, C. Hochstim, B. Deneen, D. Rowitch
37. Specification of Macroglia by Transcription Factors: Oligodendrocytes
M. Wegner
38. Specification of Macroglia by Transcription Factors: Schwann Cells
D. Meijer, J. Svaren
39. Signaling Pathways that Regulate Glial Development and Early Migration Oligodendrocytes
R.H. Miller
40. Signaling Pathways that Regulate Glial Development and Early Migration Schwann Cells
K.R. Jessen, R. Mirsky
41. Microglia
A.E. Cardona, R.M. Ransohoff, K. Akassoglou
42. Ependyma, Choroid
A. Meunier, K. Sawamoto, N. Spassky
43. Meninges and Vasculature
J.A. Siegenthaler, S.J. Pleasure
44. Neuron–Glial Interactions: Schwann Cells
M.H. Schwab, M.W. Sereda, K.-A. Nave
45. Neuron–Glial Interactions: Neurotransmitter Signaling to Cells of the Oligodendrocyte Lineage
L.M. De Biase, D.E. Bergles
46. Invertebrate Glia
T. Stork, M.R. Freeman
47. Nonmammalian Model Systems: Zebrafish
B. Appel
48. New Approaches in Glial Biology: Imaging Neuroglial Pathology In Vivo
I. Nikić, T. Misgeld, M. Kerschensteiner
Index

About the Author

Dr. Rubenstein is a Professor in the Department of Psychiatry at the University of California, San Francisco. He also serves as a Nina Ireland Distinguished Professor in Child Psychiatry at the Nina Ireland Laboratory of Developmental Neurobiology. His research focuses on the regulatory genes that orchestrate development of the forebrain. Dr. Rubenstein's lab has demonstrated the role of specific genes in regulating neuronal specification, differentiation, migration and axon growth during embryonic development and on through adult life. His work may help to explain some of the mechanisms underlying human neurodevelopmental disorders such as autism. Dr. Rakic is currently at the Yale School of Medicine, Department of Neuroscience, where his main research interest is in the development and evolution of the human brain. After obtaining his MD from the University of Belgrade School of Medicine, his research career began in 1962 with a Fulbright Fellowship at Harvard University after which he obtained his graduate degrees in Developmental Biology and Genetics. He held a faculty position at Harvard Medical School for 8 years prior to moving to Yale University, where he founded and served as Chair of the Department of Neurobiology for 37 years, and also founder and director of the Kavli Institute for Neuroscience. In 2015, he returned to work full-time on his research projects, funded by US Public Health Services and various private foundations.

He is well known for his studies of the development and evolution of the brain, in particular his discovery of basic cellular and molecular mechanisms of proliferation and migration of neurons in the cerebral cortex. He was president of the Society for Neuroscience and popularized this field with numerous lectures given in over 35 counties. In 2008, Rakic shared the inaugural Kavli Prize in Neuroscience with Thomas Jessell and Stan Grillner. He is currently the Dorys McConell Duberg Professor of Neuroscience and serves on Advisory Boards and Scientific Councils of a number of Institutions and Research Foundations.

Reviews

"This first volume of the Comprehensive Developmental Neuroscience series, presented by editors Rubenstein and Rakic, draws from developmental biology, cell biology, molecular genetics, and nervous system morphology to give a rounded picture of the course of neurological development. Intended to be useful for researchers, clinicians, and students, the text is extensive with references to primary research and contains many full-color illustrations."--Reference & Research Book News, October 2013