This volume is the first to present a framework of general principles for animal research ethics together with an analysis of the principles' meaning and moral requirements. This new framework of six moral principles constitutes a more suitable set of moral guidelines than any currently available, including the influential framework presented in the Principles of Humane Experimental Technique published in 1959 by zoologist and psychologist William M. S.
Russell and microbiologist Rex L. Burch. While other accounts have presented specific directives to guide the use of animals in research, Tom L. Beauchamp and David DeGrazia here offer a set of general moral
principles that are adequate to the task of evaluating biomedical and behavioral research involving animals today. Their comprehensive framework addresses ethical requirements pertaining to societal benefit-a critical consideration in justifying the harming of animals in research-and features a thorough program of animal welfare protection. In doing so, their principles bridge the gap between the concerns of the research community and the animal-protection community. The
book is distinctive in featuring commentaries on the framework of principles by eminent figures in animal research ethics from an array of relevant disciplines: veterinary medicine, biomedical research,
biology, zoology, comparative psychology, primatology, law, and bioethics. The seven commentators-Larry Carbone, Frans de Waal, Rebecca Dresser, Joseph Garner, Brian Hare, Margaret Landi, and Julian Savulescu-scrutinize Beauchamp and DeGrazia's principles in terms of both their theoretical cogency and practical implications, evaluating their relevance to the medical and scientific professions. The range of ethical issues encompassed in Principles of Animal Research Ethics will be
useful to professionals in the biomedical and behavioral sciences and will also appeal to individuals and scholars interested in bioethics, animal ethics, and applied ethics generally.
This volume is the first to present a framework of general principles for animal research ethics together with an analysis of the principles' meaning and moral requirements. This new framework of six moral principles constitutes a more suitable set of moral guidelines than any currently available, including the influential framework presented in the Principles of Humane Experimental Technique published in 1959 by zoologist and psychologist William M. S.
Russell and microbiologist Rex L. Burch. While other accounts have presented specific directives to guide the use of animals in research, Tom L. Beauchamp and David DeGrazia here offer a set of general moral
principles that are adequate to the task of evaluating biomedical and behavioral research involving animals today. Their comprehensive framework addresses ethical requirements pertaining to societal benefit-a critical consideration in justifying the harming of animals in research-and features a thorough program of animal welfare protection. In doing so, their principles bridge the gap between the concerns of the research community and the animal-protection community. The
book is distinctive in featuring commentaries on the framework of principles by eminent figures in animal research ethics from an array of relevant disciplines: veterinary medicine, biomedical research,
biology, zoology, comparative psychology, primatology, law, and bioethics. The seven commentators-Larry Carbone, Frans de Waal, Rebecca Dresser, Joseph Garner, Brian Hare, Margaret Landi, and Julian Savulescu-scrutinize Beauchamp and DeGrazia's principles in terms of both their theoretical cogency and practical implications, evaluating their relevance to the medical and scientific professions. The range of ethical issues encompassed in Principles of Animal Research Ethics will be
useful to professionals in the biomedical and behavioral sciences and will also appeal to individuals and scholars interested in bioethics, animal ethics, and applied ethics generally.
About the Authors and Commentators
Preface
Preamble to Principles of Animal Research Ethics
Principles of Animal Research Ethics - David DeGrazia and Tom L.
Beauchamp
The Essential Place of Moral Justification
Principles of Social Benefit
(1) The Principle of No Alternative Method
(2) The Principle of Expected Net Benefit
(3) The Principle of Sufficient Value to Justify Harm
Principles of Animal Welfare
(1) The Principle of No Unnecessary Harm
(2) The Principle of Basic Needs
(3) The Principle of Upper Limits to Harm
The Crucial Role of Ethics Review Committees
Scientific Necessity as a Justification for Causing Harm
On The Principles of Humane Experimental Technique
Critical Commentary by Authorities on Animal Research Ethics
"The Potential and Impacts of Practical Application of Beauchamp
and DeGrazia's Six Principles" Larry Carbone
"Reflections on Primates in Research" Frans B. M. de Waal
"Putting the Ethical Principles into Practice" Rebecca Dresser
"The Mouse in the Room: The Distinction Between Regulations and
Ethics" Joseph P. Garner
"Compassion for Other Animals Beyond the Human Hierarchy of
Concern" Brian Hare
"Commentary on the Beauchamp-DeGrazia Framework of Principles"
Margaret S. Landi
"The Six Principles, Philosophy, and Applying Human Ethics to
Animals" Julian Savulescu
Tom L. Beauchamp is Professor Emeritus of Philosophy and Bioethics,
Georgetown University. His research centers on biomedical ethics,
animal research ethics, and the philosophy of David Hume. His books
include Principles of Biomedical Ethics (with James Childress); A
History and Theory of Informed Consent (with Ruth Faden); Standing
on Principles: Collected Essays; Hume and the Problem of Causation
(with
Alexander Rosenberg); and five volumes of the critical edition of
David Hume's Philosophy published in Oxford University Press's
Clarendon Hume editions. From 1976-78 he drafted the bulk of The
Belmont Report for the National Commission for the Protection
of
Human Subjects. He has been given the Lifetime Achievement Award
for Excellence in Research Ethics by Public Responsibility in
Medicine and Research (PRIM&R); the Henry Beecher Award of the
Hastings Center, New York; and the Lifetime Achievement Award of
the American Society of Bioethics and Humanities (ASBH).
David DeGrazia is Elton Professor of Philosophy at George
Washington University and Senior Research Fellow in the National
Institutes of Health Department of Bioethics. DeGrazia's research
focuses primarily on applied ethics and ethical theory. His
scholarly work on animals addresses their moral status, their
consciousness and cognitive capacities, and the ethics of using
animals in research and for food. In 2018 he was named a Fellow of
the Hastings Center and the recipient
of GWU's Distinguished Scholar Award.
"Beauchamp and DeGrazia's work constitutes a remarkably clear and highly authoritative presentation of key issues in the ethical justification and assessment of animal research. The authors are towering figures in both animal and human subject research ethics, and in this must-read work, they are at their best." -- Rebecca L. Walker, Hastings Center Report
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