Stammzellen und Gentherapie erstmals in einem einzigen Band! Von den Grundlagen bis zu komplizierten Verfahren werden die Anwendungen der Stammzellbiologie zur Entwicklung von Therapien verschiedenster genetisch verursachter Krankheiten beschrieben. Der Schwerpunkt liegt auf einem der schwierigsten Aspekte der Gentherapie, den Vektoren. Ein absolutes Muß für Biotechnologen, die Gentherapeutika für den kommerziellen Einsatz entwickeln! (05/98)

Stem Cell Systems: Basic Principles and Methodologies (S. Nilsson & P. Quesenberry). Cytokine/Growth Factor Responsiveness of Early Hemopoietic Progenitor Cells (A. Burgess). Molecular Mechanisms Controlling the Cell Cycle and Proliferation-Differentiation Interrelationships (G. Stein, et al.). Stem Cell Transcription (S. Weissman & A. Perkins). Hematopoietic Stem Cells: Proliferation, Purification and Clinical Applications (R. Pettengell & M. Moore). Delivery Systems for Gene Therapy: The Adenovirus (T. Shenk). Gene Transfer to Muscle and Spinal Cord Using Herpes Simplex Virus-Based Vectors (J. Huard, et al.). Herpes Virus Vectors (X. Breakefield, et al.). Delivery Systems for Gene Therapy: Adeno-Associated Virus (G. Kroner-Lux, et al.). Delivery Systems for Gene Therapy: Adeno-Associated Virus 2 (A. Srivastava). Ribozyme Gene Therapy Targeting Stem Cells for Human Immunodeficiency Virus Infection (A. Ho, et al.). Elements of DNA Vaccine Design (M. Caufield & M. Liu). Development of Gene Therapy for Gaucher Disease (J. Barranger, et al.). Clinical Applications of Gene Therapy: Correction of Genetic Disease Affecting Hematopoietic Cells (J. Medin, et al.). Gene Therapy for Hemophilia (K. High). Clinical Applications of Gene Therapy: Anemias (G. Atweh & B. Forget). Clinical Applications of Gene Therapy in Cancer: Modification of Sensitivity to Therapeutic Agents (T. Licht, et al.). Clinical Applications of Gene Therapy: Brian Tumors (K. Culver & J. Van Gilder). Clinical Applications of Gene Therapy: Cardiovascular Disease (J. Fox). Applications of Gene Therapy to Neurological Diseases and Injuries (D. Choi-Lundberg & M. Bohn). Index.